REGULATION AND ASSEMBLY OF THE FLAGELLAR SYSTEM AND BACTERIAL POLARITY
PHENOMENA
RESEARCHERS INVOLVED:
Fernando Govantes, Aroa López-Sánchez, Marta Pulido-Sánchez, María Zapata, and Gonzalo Ariza
COLLABORATORS:
Carmen Beuzón (IHSM La Mayora-UMA), Javier Ruiz Albert (IHSM La Mayora-UMA) and María Trinidad Gallegos Fernández (Estación Experimental del Zaidín-CSIC)
SUMMARY
In this line we investigate the mechanisms of regulation of the synthesis of flagellar components, as well as the temporal, spatial and numerical regulation of flagella and other polarly localized components in bacteria of the genus Pseudomonas. Our work has allowed us to fully elucidate the transcriptional cascade responsible for the expression of flagellar and chemotaxis genes in Pseudomonas putida and many of the elements responsible for the polar localization of the flagellar and chemotaxis systems.
RELATED PUBLICATIONS
- Marta Pulido-Sánchez, Antonio Leal-Morales, Aroa López-Sánchez, Felipe Cava, Fernando Govantes. Spatial, temporal and numerical regulation of polar flagella assembly in Pseudomonas putida. Microbiol Res. 2025 Mar:292:128033; doi: 10.1016/j.micres.2024.128033.
- Leal-Morales A, Pulido-Sánchez P, López-Sánchez A and Govantes F. Transcriptional organization and regulation of the Pseudomonas putida flagellar system. Environ Microbiol. 2022 Jan;24(1):137-157. doi: 10.1111/1462-2920.15857
- Navarrete B, Leal-Morales A, Serrano-Ron L, Sarrió M, Jiménez-Fernández A, Jiménez Díaz L, López-Sánchez A and Govantes F. Transcriptional organization, regulation and functional analysis of flhF and fleN in Pseudomonas putida. PLoS One. 2019 Mar 14(3):e0214166. doi: 10.1371/journal.pone.0214166
- Wirebran L, Östeberg S, López-Sánchez A, Govantes F and Shingler V. PP4397/FlgZ provides the link between PP2258 c-di-GMP signalling and altered motility in Pseudomonas putida. Sci Rep. 2018 Aug 15;8(1):12205 doi: 10.1038/s41598-018-29785-w.
