MODELING AND COMPUTATIONAL SIMULATION OF BIOFILM DEVELOPMENT
RESEARCHERS INVOLVED:
Fernando Govantes and Marta Pulido-Sánchez
COLLABORATORS:
Alejandro Cuetos Menéndez (UPO) and Álvaro González García (UPO)
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SUMMARY
In this line we established a close collaboration with the group of Alejandro Cuetos (Universidad Pablo de Olavide) to establish computational models of various aspects of bacterial biofilm development. Our work has allowed us to establish the parameters that govern the internal organization of surface-associated colonies and the role of parameters such as diffusion and growth rates and local nutrient concentrations in these processes.
RELATED PUBLICATIONS
- Lobo-Cabrera FJ, Herrero MDR, Govantes F, Cuetos A. Computer simulation study of nutrient-driven bacterial biofilm stratification. J R Soc Interface. 2024 Jun;21(215):20230618. doi: 10.1098/rsif.2023.0618
- Lobo-Cabrera FJ, Patti A, Govantes F, Cuetos A. Polymer-induced microcolony compaction in early biofilms: A computer simulation study. Phys Rev E. 2021 May;103(5-1):052407. doi: 10.1103/PhysRevE.103.052407.
- Acemel RD, Govantes F, Cuetos A. Computer simulation study of early bacterial biofilm development. Sci Rep. 2018 Mar 28;8(1):5340. doi: 10.1038/s41598-018-23524-x. PMID: 29593289; PMCID: PMC5871757.